Ionis Pharmaceuticals Inc
NASDAQ:IONS

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Ionis Pharmaceuticals Inc Logo
Ionis Pharmaceuticals Inc
NASDAQ:IONS
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Price: 76.33 USD -1.14%
Market Cap: 12.4B USD
Financials Section:
Income Statement Balance Sheet Cash Flow Statement

Cash Flow Statement

Operating Cash Flow
+
3Y
-
5Y
-
10Y
-
Investing Cash Flow
+
3Y
-
5Y
-7%
10Y
-
Financing Cash Flow
+
3Y
-
5Y
-
10Y
-36%

Cash Flow Statement
Ionis Pharmaceuticals Inc

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Cash Flow Statement
Currency: USD
Dec-2001 Mar-2002 Jun-2002 Sep-2002 Dec-2002 Mar-2003 Jun-2003 Sep-2003 Dec-2003 Mar-2004 Jun-2004 Sep-2004 Dec-2004 Mar-2005 Jun-2005 Sep-2005 Dec-2005 Mar-2006 Jun-2006 Sep-2006 Dec-2006 Mar-2007 Jun-2007 Sep-2007 Dec-2007 Mar-2008 Jun-2008 Sep-2008 Dec-2008 Mar-2009 Jun-2009 Sep-2009 Dec-2009 Mar-2010 Jun-2010 Sep-2010 Dec-2010 Mar-2011 Jun-2011 Sep-2011 Dec-2011 Mar-2012 Jun-2012 Sep-2012 Dec-2012 Mar-2013 Jun-2013 Sep-2013 Dec-2013 Mar-2014 Jun-2014 Sep-2014 Dec-2014 Mar-2015 Jun-2015 Sep-2015 Dec-2015 Mar-2016 Jun-2016 Sep-2016 Dec-2016 Mar-2017 Jun-2017 Sep-2017 Dec-2017 Mar-2018 Jun-2018 Sep-2018 Dec-2018 Mar-2019 Jun-2019 Sep-2019 Dec-2019 Mar-2020 Jun-2020 Sep-2020 Dec-2020 Mar-2021 Jun-2021 Sep-2021 Dec-2021 Mar-2022 Jun-2022 Sep-2022 Dec-2022 Mar-2023 Jun-2023 Sep-2023 Dec-2023 Mar-2024 Jun-2024 Sep-2024 Dec-2024 Mar-2025 Jun-2025 Sep-2025
Operating Cash Flow
Net Income
(74)
0
0
0
(72)
0
0
0
(95)
0
0
0
(143)
0
0
0
(72)
0
0
0
(46)
0
0
0
(40)
0
0
0
(23)
0
0
0
151
0
0
0
(61)
0
0
0
(85)
0
0
0
(66)
(2)
(12)
0
(61)
(41)
(43)
(70)
(39)
(24)
23
14
(88)
(135)
(227)
(184)
(60)
(20)
39
24
(11)
(25)
(84)
(97)
215
317
363
402
287
147
119
64
(480)
(520)
(563)
(609)
(29)
(4)
(28)
7
(270)
(329)
(309)
(409)
(366)
(385)
(366)
(359)
(454)
(458)
(268)
(256)
Depreciation & Amortization
7
0
0
0
9
0
0
0
12
0
0
0
12
0
0
0
10
0
0
0
8
0
0
0
7
0
0
0
7
0
0
0
9
0
0
0
9
0
0
0
12
0
0
0
11
3
5
0
10
5
5
7
9
10
10
10
10
10
10
10
9
9
9
10
8
9
9
10
13
13
14
14
14
15
15
15
16
16
17
18
18
18
18
18
17
16
14
13
13
15
18
20
12
9
6
4
Change in Deffered Taxes
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
(291)
(277)
(276)
(286)
1
(15)
(13)
(2)
342
344
342
340
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
Stock-Based Compensation
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
6
2
5
7
10
11
12
13
15
14
15
14
13
14
14
13
12
12
11
10
10
9
9
9
9
9
9
10
11
16
21
26
31
38
44
50
59
66
72
74
72
73
75
79
86
94
106
120
131
148
156
146
147
142
148
170
230
227
209
193
121
109
104
97
100
101
103
105
106
110
114
120
130
129
128
127
Other Non-Cash Items
36
0
0
0
(14)
0
0
0
12
0
0
0
53
0
0
0
11
0
0
0
(18)
0
0
0
16
0
0
0
17
0
0
0
(164)
0
0
0
30
0
0
0
29
0
0
0
6
6
13
0
28
16
24
39
31
43
52
41
79
87
93
116
117
119
123
134
140
146
157
161
167
181
187
176
212
202
195
214
232
233
235
221
155
145
131
122
(29)
(20)
(35)
(23)
123
114
132
122
150
152
171
142
Cash Taxes Paid
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
10
13
21
14
11
7
(0)
(0)
(0)
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
9
9
0
24
26
26
0
2
0
0
0
0
5
5
6
6
48
48
50
50
(6)
(6)
(8)
(8)
Cash Interest Paid
4
3
36
36
39
39
10
10
13
13
12
13
9
9
9
9
9
9
9
9
8
9
8
10
6
8
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
6
6
4
7
3
6
6
6
6
6
6
7
8
7
7
7
7
7
7
8
7
8
9
9
9
10
10
10
10
10
10
8
8
6
6
6
6
5
5
3
4
3
2
2
2
7
7
12
11
11
11
11
11
Change in Working Capital
25
(5)
(53)
(95)
(17)
(97)
(64)
(73)
(24)
(101)
(110)
(109)
(24)
(100)
(88)
(72)
(9)
(55)
(50)
(58)
3
(58)
(45)
(19)
54
132
311
277
211
103
(86)
(96)
(104)
(96)
(80)
(69)
(42)
(82)
(113)
(115)
(67)
(79)
(55)
(57)
50
(9)
17
114
86
69
5
(55)
5
(32)
11
64
21
25
14
(65)
(178)
(21)
(48)
(40)
37
(65)
481
434
499
464
(118)
(123)
(169)
(118)
(102)
(76)
(74)
(84)
(60)
(45)
(114)
(105)
(22)
(17)
8
(44)
(127)
(121)
(77)
(68)
(130)
(135)
(209)
(205)
(140)
(136)
Cash from Operating Activities
(6)
N/A
(5)
+23%
(53)
-1 000%
(95)
-81%
(94)
+1%
(97)
-2%
(64)
+34%
(73)
-14%
(96)
-31%
(101)
-6%
(110)
-9%
(109)
+1%
(102)
+7%
(100)
+1%
(88)
+12%
(72)
+18%
(61)
+16%
(55)
+10%
(50)
+9%
(58)
-16%
(53)
+8%
(58)
-9%
(45)
+22%
(19)
+59%
36
N/A
132
+266%
311
+136%
277
-11%
212
-23%
103
-52%
(86)
N/A
(96)
-13%
(108)
-13%
(96)
+12%
(80)
+16%
(69)
+14%
(64)
+8%
(82)
-28%
(113)
-38%
(115)
-2%
(112)
+2%
(79)
+30%
(55)
+30%
(57)
-3%
2
N/A
(2)
N/A
23
N/A
114
+388%
64
-44%
42
-34%
(15)
N/A
(79)
-426%
6
N/A
(4)
N/A
95
N/A
129
+36%
21
-84%
(12)
N/A
(111)
-832%
(123)
-11%
(112)
+9%
86
N/A
123
+42%
127
+4%
174
+37%
65
-63%
563
+771%
508
-10%
603
+19%
697
+16%
170
-76%
183
+8%
346
+89%
230
-33%
213
-7%
216
+1%
36
-83%
(11)
N/A
(30)
-164%
(75)
-153%
31
N/A
54
+75%
98
+83%
130
+32%
(274)
N/A
(377)
-37%
(456)
-21%
(541)
-19%
(308)
+43%
(323)
-5%
(346)
-7%
(352)
-2%
(501)
-42%
(502)
0%
(231)
+54%
(247)
-7%
Investing Cash Flow
Capital Expenditures
(9)
(14)
(19)
(27)
(37)
(34)
(30)
(20)
(8)
(4)
(4)
(4)
(4)
(4)
(2)
(2)
(0)
(0)
(0)
(1)
(1)
(1)
(2)
(1)
(2)
(3)
(6)
(8)
(14)
(15)
(20)
(18)
(13)
(21)
(15)
(14)
(13)
(5)
(7)
(9)
(10)
(8)
(5)
(2)
(2)
(2)
(1)
(2)
(2)
(3)
(4)
(5)
(8)
(7)
(8)
(9)
(8)
(7)
(7)
(7)
(7)
(10)
(13)
(29)
(35)
(34)
(34)
(21)
(14)
(15)
(12)
(25)
(31)
(37)
(42)
(38)
(35)
(28)
(23)
(15)
(12)
(13)
(12)
(14)
(16)
(24)
(32)
(29)
(24)
(18)
(12)
(19)
(45)
(53)
(59)
(56)
Other Items
(134)
(142)
(145)
(26)
(24)
(30)
24
2
(8)
49
33
57
87
63
62
60
48
46
38
38
(32)
(56)
(33)
(98)
(53)
(44)
(105)
(208)
(221)
(335)
(330)
(210)
(199)
(47)
(85)
30
37
70
157
78
118
59
55
48
20
5
(52)
(164)
(254)
(213)
(212)
(113)
(75)
(64)
(126)
(130)
(52)
(50)
99
70
64
(142)
(177)
(254)
(324)
(76)
(466)
(637)
(916)
(1 065)
(803)
(481)
(10)
(29)
166
263
310
476
291
302
207
(159)
(62)
(366)
(247)
(277)
(196)
54
(190)
205
193
(210)
(89)
14
(163)
266
Cash from Investing Activities
(144)
N/A
(156)
-9%
(164)
-5%
(53)
+68%
(60)
-14%
(64)
-6%
(6)
+90%
(19)
-198%
(15)
+18%
45
N/A
29
-35%
53
+81%
84
+59%
59
-30%
59
+1%
58
-2%
47
-19%
46
-3%
38
-18%
37
-1%
(33)
N/A
(57)
-76%
(35)
+40%
(99)
-188%
(56)
+44%
(47)
+16%
(110)
-136%
(216)
-96%
(234)
-9%
(350)
-50%
(350)
+0%
(228)
+35%
(212)
+7%
(68)
+68%
(100)
-46%
16
N/A
24
+51%
65
+176%
150
+130%
69
-54%
108
+58%
51
-53%
50
-1%
45
-10%
18
-60%
3
-82%
(53)
N/A
(166)
-214%
(256)
-55%
(216)
+16%
(216)
0%
(117)
+46%
(83)
+29%
(71)
+14%
(134)
-89%
(139)
-4%
(60)
+57%
(57)
+4%
92
N/A
64
-30%
57
-11%
(152)
N/A
(190)
-26%
(283)
-49%
(358)
-26%
(110)
+69%
(500)
-354%
(658)
-32%
(930)
-41%
(1 079)
-16%
(815)
+25%
(506)
+38%
(41)
+92%
(66)
-60%
124
N/A
225
+81%
275
+22%
448
+63%
268
-40%
288
+8%
195
-32%
(172)
N/A
(74)
+57%
(380)
-414%
(263)
+31%
(301)
-15%
(228)
+24%
25
N/A
(214)
N/A
188
N/A
181
-4%
(229)
N/A
(134)
+41%
(40)
+70%
(222)
-460%
210
N/A
Financing Cash Flow
Net Issuance of Common Stock
211
212
193
116
9
8
3
3
2
3
3
3
4
2
2
50
49
52
52
9
86
85
85
94
21
73
74
65
63
26
26
22
23
8
7
5
4
4
4
4
4
4
4
10
10
21
218
232
236
237
40
24
23
25
28
26
25
14
11
12
13
88
90
205
205
133
582
472
476
537
120
122
141
(9)
(35)
(32)
(39)
52
135
124
101
95
5
6
6
7
8
9
49
70
71
563
523
501
500
85
Net Issuance of Debt
27
34
122
113
121
122
42
51
40
32
23
19
8
11
5
(4)
(12)
(16)
(13)
(8)
(8)
104
22
22
22
(90)
(3)
(4)
5
9
5
12
4
0
3
(1)
0
(0)
(2)
(3)
(4)
(5)
1
31
30
29
22
(9)
(9)
(8)
(11)
(11)
35
35
35
36
(1)
0
1
5
(3)
(3)
(3)
(26)
(24)
(22)
(21)
0
0
0
0
(13)
97
0
97
110
0
0
376
376
314
0
(62)
(62)
(51)
(51)
104
36
87
87
(68)
(0)
(45)
(45)
(45)
(45)
Other
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
71
71
71
71
0
0
0
20
40
40
40
195
175
175
175
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
2
0
0
0
0
0
0
(1)
1
1
1
52
48
48
49
(1)
0
(7)
(8)
(19)
(138)
(142)
(142)
(134)
(558)
(562)
(714)
(713)
(169)
(163)
(11)
(11)
(11)
488
475
507
508
18
32
0
0
0
0
0
Cash from Financing Activities
237
N/A
245
+4%
314
+28%
229
-27%
130
-43%
129
0%
45
-65%
54
+20%
42
-23%
35
-17%
26
-25%
22
-14%
12
-45%
14
+11%
7
-51%
46
+597%
38
-18%
36
-4%
110
+205%
72
-35%
150
+108%
260
+74%
107
-59%
116
+8%
44
-62%
3
-92%
112
+3 285%
101
-9%
108
+6%
230
+114%
206
-11%
209
+1%
202
-3%
9
-96%
10
+16%
5
-55%
5
+4%
4
-17%
2
-51%
1
-26%
(1)
N/A
(2)
-171%
6
N/A
41
+630%
39
-4%
50
+28%
240
+379%
223
-7%
228
+2%
228
+0%
29
-87%
13
-55%
60
+358%
62
+4%
64
+4%
63
-2%
25
-61%
14
-43%
12
-13%
17
+35%
11
-31%
86
+654%
88
+3%
231
+162%
229
-1%
159
-31%
610
+284%
471
-23%
476
+1%
530
+11%
112
-79%
91
-19%
100
+10%
(54)
N/A
(80)
-48%
(56)
+30%
(597)
-967%
(510)
+15%
(204)
+60%
(213)
-5%
246
N/A
246
+0%
(67)
N/A
(67)
+1%
(55)
+17%
444
N/A
586
+32%
552
-6%
644
+17%
176
-73%
35
-80%
563
+1 526%
478
-15%
457
-4%
455
0%
41
-91%
Change in Cash
Effect of Foreign Exchange Rates
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
1
1
1
1
0
(0)
(0)
(1)
(1)
(0)
(0)
0
1
0
0
0
1
(0)
0
1
0
Net Change in Cash
87
N/A
84
-3%
97
+15%
81
-17%
(25)
N/A
(32)
-25%
(25)
+22%
(37)
-51%
(69)
-84%
(21)
+69%
(55)
-158%
(34)
+38%
(6)
+83%
(28)
-369%
(22)
+19%
32
N/A
24
-25%
27
+12%
98
+267%
51
-48%
64
+25%
145
+127%
28
-81%
(2)
N/A
24
N/A
89
+267%
313
+253%
163
-48%
85
-47%
(18)
N/A
(230)
-1 184%
(115)
+50%
(119)
-3%
(155)
-31%
(170)
-9%
(49)
+71%
(35)
+28%
(12)
+65%
39
N/A
(45)
N/A
(5)
+90%
(30)
-550%
1
N/A
29
+4 783%
59
+101%
51
-13%
211
+311%
172
-19%
36
-79%
54
+52%
(203)
N/A
(183)
+10%
(17)
+91%
(13)
+21%
26
N/A
54
+110%
(14)
N/A
(55)
-286%
(7)
+87%
(43)
-499%
(44)
-4%
21
N/A
21
-2%
75
+265%
45
-40%
113
+152%
672
+493%
321
-52%
149
-53%
148
-1%
(533)
N/A
(232)
+56%
404
N/A
110
-73%
258
+134%
385
+49%
(286)
N/A
(72)
+75%
35
N/A
(0)
N/A
472
N/A
128
-73%
(43)
N/A
(318)
-635%
(593)
-86%
(233)
+61%
(97)
+58%
37
N/A
123
+230%
40
-68%
(131)
N/A
(17)
+87%
(157)
-800%
(85)
+46%
3
N/A
4
+13%
Free Cash Flow
Free Cash Flow
(16)
N/A
(19)
-24%
(72)
-273%
(123)
-71%
(131)
-7%
(131)
+0%
(94)
+29%
(93)
+1%
(103)
-11%
(105)
-2%
(114)
-8%
(113)
+1%
(105)
+7%
(104)
+1%
(91)
+13%
(74)
+19%
(61)
+17%
(55)
+10%
(50)
+9%
(59)
-17%
(54)
+8%
(59)
-9%
(47)
+21%
(20)
+57%
34
N/A
129
+281%
306
+137%
269
-12%
198
-26%
87
-56%
(105)
N/A
(115)
-9%
(122)
-6%
(117)
+4%
(95)
+18%
(84)
+12%
(77)
+8%
(87)
-13%
(120)
-39%
(124)
-3%
(122)
+2%
(87)
+29%
(60)
+30%
(59)
+2%
0
N/A
(4)
N/A
22
N/A
113
+407%
62
-45%
39
-37%
(19)
N/A
(83)
-337%
(1)
+99%
(11)
-833%
87
N/A
121
+39%
13
-89%
(19)
N/A
(118)
-511%
(130)
-10%
(119)
+8%
77
N/A
109
+42%
98
-11%
139
+43%
31
-78%
528
+1 621%
487
-8%
589
+21%
683
+16%
158
-77%
159
+0%
315
+98%
194
-39%
171
-11%
178
+4%
1
-100%
(39)
N/A
(53)
-35%
(90)
-70%
19
N/A
41
+118%
87
+111%
115
+33%
(290)
N/A
(400)
-38%
(488)
-22%
(569)
-17%
(331)
+42%
(341)
-3%
(358)
-5%
(371)
-4%
(546)
-47%
(555)
-2%
(290)
+48%
(303)
-4%

See Also

Summary
IONS intrinsic value, competitors valuation, and company profile.
DCF Valuation
IONS stock valuation using Discount Cash Flow valuation method.
Relative Valuation
IONS stock valuation using valuation multiples.
Wall Street Estimates
IONS price targets and financial estimates made by Wall st analysts.
Profitability Analysis
Detailed analysis of the company's profitability.
Solvency Analysis
Analysis of the financial position and solvency of the company.
Financials
Income Statement, Balance Sheet, Cash Flow Statement.
Discount Rate
IONS stock discount rate: cost of equity and WACC.
Summary
DCF Valuation
Relative Valuation
Wall Street Estimates
Profitability Analysis
Solvency Analysis
Financials
Discount Rate
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