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Astellas Pharma Inc
TSE:4503

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Astellas Pharma Inc
TSE:4503
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Price: 2 525 JPY -1.75% Market Closed
Market Cap: ¥4.6T

EV/EBITDA

7.8
Current
27%
Cheaper
vs 3-y average of 10.6

Enterprise Value to EBITDA (EV/EBITDA) ratio compares a company`s total enterprise value to its earnings before interest, taxes, depreciation, and amortization. It shows how much investors are paying for each dollar of the company`s earnings, including both equity and debt.

EV/EBITDA
7.8
=
Enterprise Value
¥4.6T
/
EBITDA
¥586.5B

Enterprise Value to EBITDA (EV/EBITDA) ratio compares a company`s total enterprise value to its earnings before interest, taxes, depreciation, and amortization. It shows how much investors are paying for each dollar of the company`s earnings, including both equity and debt.

EV/EBITDA
7.8
=
Enterprise Value
¥4.6T
/
EBITDA
¥586.5B

Valuation Scenarios

Astellas Pharma Inc is trading below its 3-year average

If EV/EBITDA returns to its 3-Year Average (10.6), the stock would be worth ¥3 451.61 (37% upside from current price).

Statistics
Positive Scenarios
4/4
Maximum Downside
No Downside Scenarios
Maximum Upside
+42%
Average Upside
32%
Scenario EV/EBITDA Value Implied Price Upside/Downside
Current Multiple 7.8 ¥2 525
0%
3-Year Average 10.6 ¥3 451.61
+37%
5-Year Average 11.1 ¥3 591.79
+42%
Industry Average 10.6 ¥3 440.61
+36%
Country Average 8.7 ¥2 810.63
+11%

Forward EV/EBITDA
Today’s price vs future ebitda

Today's Enterprise Value EBITDA Forward EV/EBITDA
¥4.6T
/
Jan 2026
¥586.5B
=
7.8
Current
¥4.6T
/
Mar 2026
¥611.5B
=
7.5
Forward
¥4.6T
/
Mar 2027
¥681.9B
=
6.7
Forward
¥4.6T
/
Mar 2028
¥639.1B
=
7.2
Forward

Forward EV/EBITDA shows whether today’s EV/EBITDA still looks high or low once future ebitda are taken into account.

Peer Comparison

All Multiples
EV/EBITDA
P/E
All Countries
Close
Market Cap EV/EBITDA P/E
JP
Astellas Pharma Inc
TSE:4503
4.5T JPY 7.8 14
US
Eli Lilly and Co
NYSE:LLY
853.2B USD 28 41.3
US
Johnson & Johnson
NYSE:JNJ
544.6B USD 16.6 25.9
CH
Roche Holding AG
SIX:ROG
248.4B CHF 11.7 19.8
UK
AstraZeneca PLC
LSE:AZN
225.8B GBP 16.2 29.2
CH
Novartis AG
SIX:NOVN
226.8B CHF 12.3 19.9
US
Merck & Co Inc
NYSE:MRK
278.5B USD 9.5 15.3
IE
Endo International PLC
LSE:0Y5F
244.4B USD 386.8 -83.6
DK
Novo Nordisk A/S
CSE:NOVO B
1.1T DKK 8 10.9
US
Pfizer Inc
NYSE:PFE
155.3B USD 7.7 20
US
Bristol-Myers Squibb Co
NYSE:BMY
119.6B USD 7.2 17
EV/EBITDA Multiple
EBITDA Growth EV/EBITDA to Growth
JP
Astellas Pharma Inc
TSE:4503
Average EV/EBITDA: 46.5
7.8
11%
0.7
US
Eli Lilly and Co
NYSE:LLY
28
21%
1.3
US
Johnson & Johnson
NYSE:JNJ
16.6
8%
2.1
CH
Roche Holding AG
SIX:ROG
11.7
6%
2
UK
AstraZeneca PLC
LSE:AZN
16.2
12%
1.3
CH
Novartis AG
SIX:NOVN
12.3
5%
2.5
US
Merck & Co Inc
NYSE:MRK
9.5
4%
2.4
IE
E
Endo International PLC
LSE:0Y5F
386.8
N/A N/A
DK
Novo Nordisk A/S
CSE:NOVO B
8
2%
4
US
Pfizer Inc
NYSE:PFE
7.7
-8%
N/A
US
Bristol-Myers Squibb Co
NYSE:BMY
7.2
-10%
N/A
P/E Multiple
Earnings Growth PEG
JP
Astellas Pharma Inc
TSE:4503
Average P/E: 21.3
14
83%
0.2
US
Eli Lilly and Co
NYSE:LLY
41.3
32%
1.3
US
Johnson & Johnson
NYSE:JNJ
25.9
8%
3.2
CH
Roche Holding AG
SIX:ROG
19.8
14%
1.4
UK
AstraZeneca PLC
LSE:AZN
29.2
25%
1.2
CH
Novartis AG
SIX:NOVN
19.9
14%
1.4
US
Merck & Co Inc
NYSE:MRK
15.3
14%
1.1
IE
E
Endo International PLC
LSE:0Y5F
Negative Multiple: -83.6 N/A N/A
DK
Novo Nordisk A/S
CSE:NOVO B
10.9
0%
N/A
US
Pfizer Inc
NYSE:PFE
20
22%
0.9
US
Bristol-Myers Squibb Co
NYSE:BMY
17
16%
1.1

Market Distribution

In line with most companies in Japan
Percentile
41st
Based on 5 051 companies
41st percentile
7.8
Low
0.1 — 6.7
Typical Range
6.7 — 12.2
High
12.2 —
Distribution Statistics
Japan
Min 0.1
30th Percentile 6.7
Median 8.7
70th Percentile 12.2
Max 214 699 781.2

Astellas Pharma Inc
Glance View

Astellas Pharma Inc., a beacon in Japan's pharmaceutical landscape, weaves its narrative from a rich tapestry of innovation and strategic acumen. Born from the 2005 merger of Yamanouchi Pharmaceutical Co., Ltd. and Fujisawa Pharmaceutical Co., Ltd., Astellas quickly established itself as a global powerhouse based in Tokyo. The company operates primarily by investing heavily in R&D to drive breakthroughs in life sciences, particularly focusing on therapeutic areas like oncology, urology, immunology, and transplant-related therapies. Through these focal points, Astellas channels its resources to cultivate novel treatments that address unmet medical needs, thereby enhancing the quality of life for patients worldwide. The financial architecture of Astellas Pharma is underpinned by its strategic prowess in expanding its product pipelines and leveraging partnerships to amplify its reach. Revenue generation primarily hinges on its robust product offerings, spearheaded by successful medications such as XTANDI for prostate cancer and Prograf, which aids in organ transplantation outcomes. This diversified product portfolio is complemented by an astute approach to global market penetration, where Astellas not only markets these pharmaceuticals but also strategically collaborates with biotech firms and research institutions to harness cutting-edge technologies. This business model not only propels profitability but also ensures that Astellas remains at the forefront of medical innovation, positioning itself as a pivotal entity within the pharmaceutical industry.

Intrinsic Value
2 056.31 JPY
Overvaluation 19%
Intrinsic Value
Price ¥2 525
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