Enterprise Products Partners LP
NYSE:EPD
Enterprise Products Partners LP
Enterprise Products Partners LP stands as a formidable player in the midstream energy sector, weaving a complex web that interconnects the expansive North American energy landscape. Founded in 1968, this Houston-based company has evolved into one of the largest publicly traded partnerships in the United States. The company's foundational strength is rooted in its vast network of natural gas, natural gas liquids (NGLs), crude oil, and petrochemical pipelines. These pipelines stretch over tens of thousands of miles, connecting production sites to refining facilities, and ultimately the end markets, ensuring that energy products move seamlessly from the point of extraction to where they are most needed. The firm not only owns these pipelines but also storage facilities, processing plants, and export terminals, each playing a crucial role in making sure the energy products are accessible in local and international markets alike.
The genius of Enterprise Products Partners' business model lies in its fee-based revenue structure. Instead of relying heavily on the often volatile commodity prices, the company earns stable, predictable cash flows by charging fees for the transportation, storage, and processing of energy resources. This strategy allows Enterprise to mitigate risks associated with market fluctuations while capitalizing on the steady demand for energy infrastructure. The firm continually invests in expanding and modernizing its infrastructure to meet growing market demands and regulatory standards, further entrenching itself as a critical component of the energy supply chain. Through a mix of strategic acquisitions and organic growth, Enterprise not only maximizes efficiencies but also unlocks new avenues for value creation, underscoring its reputation as an indispensable bridge in the American energy ecosystem.
Earnings Calls
Cencora kicked off fiscal 2025 with impressive momentum, reporting a 13% revenue increase to $81.5 billion and a 14% rise in adjusted EPS to $3.73. The U.S. Healthcare Solutions segment led the charge with a 14% revenue surge, bolstered by strong GLP-1 sales. Guidance has been updated, projecting 8% to 10% overall revenue growth, and specifically, 9% to 11% for U.S. solutions, increased from earlier estimates. This reflects strategic acquisitions, including RCA, and efficiency gains, although some COVID-19 vaccine sales headwinds persist. Despite a challenging second quarter anticipated due to high interest expenses, optimism remains robust for continued operational growth.
Management
W. Randall Fowler is a prominent executive in the energy sector, serving as Co-Chief Executive Officer and Chief Financial Officer of Enterprise Products Partners LP, one of the leading midstream energy service providers. Fowler has been with Enterprise for several decades, playing a critical role in the company's financial and strategic planning. He joined the company in 1999, initially serving in various leadership positions within the financial division. Over time, he rose through the ranks due to his expertise and leadership skills, eventually being appointed CFO in 2007. Fowler has been instrumental in directing Enterprise's financial strategies and guiding its capital allocation, mergers and acquisitions, and funding activities. In 2018, Fowler took on the additional role of Co-CEO, alongside A. J. “Jim” Teague, further expanding his responsibilities in leading the company's strategic growth initiatives and overall operations. Under his leadership, Enterprise Products has continued to grow its vast network of pipelines and storage facilities, solidifying its position as a key player in the energy infrastructure industry. Fowler is known for his deep industry knowledge, strategic insight, and commitment to fostering a strong financial foundation and sustainable growth for Enterprise. He holds a Bachelor’s degree in accounting from the University of Alabama. His leadership is characterized by a strong focus on operational excellence, financial discipline, and a commitment to safety and environmental stewardship.
Richard Daniel Boss is currently the Executive Vice President and Chief Legal Officer at Enterprise Products Partners LP. With an extensive background in corporate law, he has played a crucial role in providing legal counsel and strategic direction to the company. Prior to joining Enterprise Products, Boss accrued a wealth of experience in the legal domain, focusing on energy sector transactions and compliance. He is known for his expertise in navigating complex legal issues and has been instrumental in supporting the company's growth and governance initiatives. His leadership extends beyond legal responsibilities, encompassing broader executive functions that contribute to the organization's overall success. Boss holds a distinguished academic background in law, further anchoring his proficiency and reputation in the industry.
Graham W. Bacon is a prominent executive at Enterprise Products Partners LP, a leading provider of energy services in North America. He serves as the Executive Vice President and Chief Operating Officer, a role in which he oversees the company's operations, ensuring efficiency and reliability in the delivery of energy solutions. Bacon has been with Enterprise for several years, bringing a vast amount of experience and expertise to his role. Throughout his tenure, he has been instrumental in driving the company's operational strategies and growth initiatives. He has a comprehensive understanding of the energy industry and is known for his leadership skills and commitment to innovation. Under his leadership, Enterprise Products Partners has focused on optimizing its expansive network of pipelines and facilities, maintaining high standards of safety, and enhancing its technological capabilities. Bacon's contributions are key to the company's efforts in adapting to the evolving demands of the energy sector and maintaining its competitive edge. Bacon holds a degree in Chemical Engineering from Texas A&M University, which provides a solid foundation for his technical and managerial responsibilities at Enterprise. His career at the company has seen him rise through various roles, thanks to his dedication and strategic vision. Overall, Graham W. Bacon is recognized for his insightful leadership and his ability to navigate complex challenges in the energy industry, contributing significantly to the success and reputation of Enterprise Products Partners LP.
Brent B. Secrest is a key executive at Enterprise Products Partners L.P., a leading North American provider of midstream energy services. He serves as the Executive Vice President and Chief Commercial Officer (CCO) of the company. In this role, Secrest is responsible for overseeing the commercial activities of the partnership, including the development of strategies to enhance the company's customer relationships, expand its business opportunities, and drive revenue growth. Prior to becoming the Chief Commercial Officer, Secrest held various leadership positions within Enterprise Products Partners. He joined the company in 1999 and has accumulated extensive experience in the energy sector over the years, contributing significantly to the company's success. His roles have included responsibilities in both commercial and operational aspects, allowing him to gain a comprehensive understanding of the company's infrastructure and business dynamics. Secrest is recognized for his strategic vision and leadership abilities, which have been instrumental in navigating the complexities of the energy industry. His contributions have helped Enterprise maintain its position as one of the leading companies in the midstream sector. Furthermore, his commitment to fostering strong client relationships and exploring new market opportunities underscores his dedication to the company's long-term growth and sustainability.
John R. Burkhalter serves as the Executive Vice President, Engineering & Asset Optimization at Enterprise Products Partners L.P., a leading North American provider of midstream energy services. With extensive expertise in the energy sector, Mr. Burkhalter oversees the engineering and asset management processes critical for optimizing the performance and efficiency of the company's vast network of energy infrastructure. His role involves strategic planning and execution to ensure that the assets operate at peak efficiency and the facilities are maintained to the highest standards. Under his leadership, Enterprise Products Partners advances its engineering innovations and sustains its reputation for operational excellence. Mr. Burkhalter's contributions significantly drive the company's growth and development in the competitive energy market.
Harry P. Weitzel, J.D., serves as the General Counsel at Enterprise Products Partners L.P., a leading North American provider of midstream energy services. Holding the position since January 2010, he plays a critical role in overseeing the company’s legal affairs. Weitzel's responsibilities at Enterprise have included a wide range of legal matters such as mergers and acquisitions, corporate governance, securities regulation, and litigation management, among others. Weitzel brings a robust background in law to his role. Before joining Enterprise, he was a partner at the Houston office of Baker Botts L.L.P., a prestigious global law firm known for its work in the energy sector. There, he gained substantial experience in corporate law and legal issues pertinent to the energy industry, which he has effectively translated into his work at Enterprise Products Partners. His legal expertise, combined with extensive industry experience, contributes significantly to the strategic and regulatory functions of Enterprise Products. As a key executive, Weitzel is instrumental in ensuring that the company's operations comply with the legal and regulatory frameworks governing the energy sector. His leadership in these areas supports Enterprise Products' mission to deliver value through operational excellence and sustainable growth in the energy infrastructure sector.
Karen D. Taylor serves as a Senior Vice President and the Chief Accounting Officer at Enterprise Products Partners LP. With extensive experience in finance and accounting, she has been with the company for several years, contributing significantly to its financial oversight and strategic planning. In her role, she is responsible for leading the accounting functions, ensuring the integrity of financial reporting, and maintaining compliance with regulatory standards. Taylor's leadership in financial operations has been integral to Enterprise Products Partners LP's growth and success, supporting its position as a leader in the energy sector. Her expertise and dedication have been recognized within the organization and the industry.
Anthony C. Chovanec is a prominent executive at Enterprise Products Partners LP, one of the leading North American providers of midstream energy services. He serves as a Senior Vice President, responsible for managing Enterprise's fundamental analysis group. Chovanec's role involves providing comprehensive analysis and insights on energy markets, which is crucial for the company's strategic decision-making and long-term planning. With extensive experience in the energy sector, Mr. Chovanec plays a pivotal role in assessing market trends and economic factors that influence the energy industry. His expertise aids Enterprise Products in optimizing its operations across various segments, including natural gas, crude oil, and petrochemicals. Prior to his tenure at Enterprise, he accumulated valuable industry experience which contributed significantly to his capabilities in overseeing market analysis and strategy development for the company. Mr. Chovanec holds a degree in Mechanical Engineering from Texas A&M University, reflecting his strong technical foundation which complements his strategic role in the industry.
Robert D. Sanders serves as the Executive Vice President and Chief Operating Officer at Enterprise Products Partners L.P., one of the largest publicly traded partnerships and a leading North American provider of midstream energy services. He plays a crucial role in overseeing the company's operations and its vast network of pipelines, processing plants, and storage facilities. Sanders has extensive experience in the energy sector and has been with Enterprise Products for several years, rising through the ranks to hold multiple key leadership positions. His deep understanding of the industry and commitment to operational excellence have been instrumental in driving Enterprise's growth and success. Under his leadership, Enterprise has continued to expand its infrastructure and capabilities in transportation, storage, and refining of natural gas and crude oil. Sanders is known for his strategic vision and focus on ensuring the reliability and efficiency of the company’s operations to meet the growing demands of the energy market.
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Hello, and welcome, everyone, to the Syncora Q1 Fiscal Year 2025 Earnings Call. My name is Becky, and I'll be your operator today. [Operator Instructions] I will now hand over to your host, Head of Investor Relations, Bennett Murphy, to begin. Please go ahead.
Thank you. Good morning, good afternoon, and thank you all for joining us for this conference call to discuss Cencora's fiscal 2025 first quarter results. I am Bennett Murphy, Senior Vice President, Head of Investor Relations and Treasury. Joining me today are Bob Mauch President and CEO; and Jim Cleary, [indiscernible] Vice President and CFO. On today's call, we will be discussing non-GAAP financial measures. Reconciliations of these measures to GAAP are provided in today's press release, which is available on our website at investor.cencora.com. .
We have also posted a slide presentation to accompany today's press release on our investor website. During this conference call, we will make forward-looking statements about our business and financial expectations on an adjusted non-GAAP basis including, but not limited to, EPS, operating income and income taxes. Forward-looking statements are based on management's current expectations and are subject to uncertainty and change. For a discussion of key risks and assumptions, we refer to today's press release and our SEC filings, including our most recent 10-K. Syncora assumes no obligation to update any forward-looking statements, and this call cannot be rebroadcast without the expressed permission of the company.
[Operator Instructions] With that, I'll turn the call over to Bob.
Thank you, Bennett. Hi, everyone, and thank you for joining Cencora's fiscal 2025 first quarter earnings call. Before we begin, I want to thank the 40-plus thousand global Cencora team members. It's because of their purpose-driven approach expertise and dedication to meeting the needs of customers and patients worldwide that Jim and I have the pleasure of reporting strong Q1 results and updated guidance today.
Cencora delivered a strong start to our fiscal year. with revenue growth of 13% and adjusted EPS growth of 14%. We are also excited to share that due to the strength in execution in our U.S. business, we are raising guidance for the fiscal year. We benefit from our position as a leading health care solutions provider with a pharmaceutical-centric strategy and a purpose-driven culture, which enables us to capitalize on positive industry trends and innovation.
Today, I will emphasize 3 areas of progress in executing our strategy and driving performance in the quarter. First, advancing our leadership in specialty where we took important steps forward. Second, driving efficiency and productivity through advanced technology and expert teams across the enterprise. And third, executing with a customer-centric mindset as we continue to collaborate and innovate with our customers throughout the supply chain.
I'll begin with advancing our leadership in specialty. Our leadership supporting specialty providers is a key differentiator and growth driver for Cencora and we've evolved our service offerings over time. Over decades, we've deepened our relationships with our specialty provider customers with the expansion of specialty GPOs and other capabilities. The logical next step is through managed service organizations. This is in line with our long-term commitment to support community providers and extension of that work. After expanding significant time understanding the MSO business through our investment in One Oncology, we announced the acquisition of RCA, Retina Consultants of America, and we are incredibly happy to have completed that acquisition on January 2.
RCA is a leading retina MSO and differentiated by its leadership team, clinical excellence, premier physician partner practices and positioning at the forefront of retina innovation through its clinical research capabilities. This acquisition, like our investment in OneOncology fits squarely into our strategy and growth by expanding our leadership in specialty in a high-growth pharmaceutical-centric segment building on our services for our customers and positioning us well in a medical specialty that has seen significant innovation.
While it's early days, we're excited about what we believe our combined organizations will accomplish together. Next is driving efficiency and productivity through advanced technology and expert teams. We are focused on continuously enhancing our capabilities and increasing efficiency through advanced technology and collaboration across our global teams.
Across the organization, we are working to streamline operations optimize business processes and unlock enterprise-wide value. In the quarter, we worked throughout our business to upgrade systems to safeguard the resiliency of our infrastructure and ensure we maintain best-in-class standards. This allows us to streamline our operations for enhanced customer satisfaction. All of this aligned with our digital transformation strategy, focuses on enhancing customer experience and accelerating decision-making as we leverage global talent and capabilities to enhance efficiency, scalability and innovation.
All while meeting the needs of our partners, both now and in the future. And finally, executing with a customer-centric mindset and innovating with our customers. At Cencora, we lead with market leaders. Our portfolio of customers is second to none, driving innovation through drug development, elevating patient care and access through their patient-first approaches. Cencora team members with world-class expertise are working in cross-functional teams collaborating with customers to meet their evolving needs. In the quarter, we were able to display solutions created as a result of working closely with our customers at our inaugural product showcase.
Our product showcase enabled us to demonstrate advanced solutions in areas like inventory planning and management, specialty GPO, and as well as cell therapy and gene therapy solutions. Another example is our enterprise leadership team just returned from the United Kingdom, visiting elements of our international operations spending time on the ground with our leaders and engaging with several top biopharma customers.
Our global footprint and expertise set us apart and gives us the unique ability to combine local expertise with global infrastructure, best meeting the needs of biopharma companies. We are focusing on building on our strengths and value proposition to pharma with our services like market access, regulatory, pharmacovigilance and our unparalleled 3PL and specialty logistics networks. This differentiated approach is strategically important to our biopharma customer relationships over the long term and it's how we capitalize on growth of specialty products in the European market, which has a different structure than in the U.S. but is similar and that our foundation in pharmaceutical distribution and portfolio of services enables us to support pharmaceutical innovation while growing our higher growth, higher-margin services.
In closing, and before I hand it over to Jim, Cencora performance is powered by an amazing global workforce who are advancing our leadership in specialty, driving efficiency and productivity through advanced technology and expert teams and executing with a customer-centric mindset as we continue to collaborate and innovate with our customers.
Looking ahead, we will maintain focus, executing against our strategy and amplifying the areas that are fundamental to our success, driving increased value for all our stakeholders. Thank you once again to all Cencora team members. And with that, I'll turn the call over to Jim for an in-depth review of our first quarter results and our updated fiscal 2025 guidance.
Thanks, Bob. Good morning, and good afternoon, everyone. As a reminder, before I turn to my prepared remarks, Unless otherwise stated, my remarks today will focus on our adjusted non-GAAP financial results. For a detailed discussion of our GAAP results, please refer to our earnings press release and presentation. Cencora delivered strong results in the first quarter of fiscal 2025 as our U.S. Healthcare Solutions segment outperformed expectations due to strong prescription utilization trends and we capitalized on the growth of our industry, the continued momentum of our business and the expertise of our teams.
As Bob mentioned, adjusted diluted EPS increased 14% and to $3.73 in the first quarter. And for the second time in fiscal 2025, we are raising our adjusted diluted EPS guidance for the full year. I'll now turn to a review of our consolidated first quarter results, starting with revenue. Our consolidated revenue was $81.5 billion, up 13% and primarily due to strong revenue growth in the U.S. Healthcare Solutions segment as we continue to benefit from overall market and volume growth, including increased sales of GLP-1 products. Excluding sales of GLP-1s, our consolidated revenue growth would have been 9%.
Turning now to gross profit. Consolidated gross profit was $2.5 billion, up 6% and with growth in both the U.S. and International Healthcare Solutions segments. Consolidated gross profit margin was 3.11%, a decrease of 20 basis points driven by the continued increase in sales of low-margin GLP-1 products combined with lower sales of commercial COVID-19 vaccines and a lack of sales of exclusive COVID-19 therapies all of which negatively impacted our gross profit margin versus the prior year quarter.
Moving now to operating expenses. In the quarter, consolidated operating expenses were $1.6 billion, up approximately 6% due to higher distribution, selling and administrative expenses to support revenue growth. Consolidated operating income was $949 million, an increase of 7% compared to the prior year quarter primarily due to 10% growth in the U.S. Healthcare Solutions segment, which I will discuss in more detail in the segment level results.
Moving now to our net interest expense and effective tax rate for the first quarter Net interest expense was $28 million, down 31% due to higher interest income resulting from higher average investment cash balances and interest rates partially offset by an increase in interest expense.
Turning now to income taxes. Our effective income tax rate was 20% compared to 21% in the prior year quarter. Finally, our diluted share count was 195.2 million shares, a 3% decline compared to the prior year first quarter driven by approximately $1.5 billion of opportunistic share repurchases during the period of February through October of 2024. As a reminder, as it relates to capital allocation, in the near term, we will prioritize deleveraging given the recent RCA acquisition. Regarding our cash balance and adjusted free cash flow, we used $2.7 billion of cash in our operations during the quarter, resulting in negative adjusted free cash flow of $2.8 billion due to the timing of flows at the end of the calendar year. We continue to expect full year adjusted free cash flow to be in the range of $2 billion to $3 billion. This completes the review of our consolidated results.
Now I'll turn to our segment results for the first quarter. U.S. Healthcare Solutions segment revenue was $74 billion, up 14% as we continued to see broad-based strong utilization trends including continued volume growth in GLP-1s and growth in sales to specialty position practices and health systems. In the quarter, sales of GLP-1 products were up $3.2 billion representing a 53% increase year-over-year. Excluding sales of GLP-1 products, U.S. segment revenue growth would have been 10% for the quarter.
U.S. Healthcare Solutions segment operating income increased 10% to $767 million, driven by growth at our Human Health distribution businesses, including specialty products and across commercial segments, including Animal Health, more than offsetting the significant headwind from lower sales of COVID-19 vaccines and lack of sales of exclusive COVID-19 therapies in the current year quarter. To provide a little more detail on the headwinds in the first quarter of fiscal 2025, the contribution from COVID-19 vaccines was about half that of the prior year quarter. and we expect a similar sized operating income headwind in the second quarter of fiscal 2025, meaning no significant expected contribution from COVID vaccines in our second quarter of fiscal 2025.
And as it relates to exclusive therapies, as a reminder, the first quarter of fiscal 2024 was the final quarter of contribution from exclusive COVID-19 therapies which contributed $0.06 to our first quarter of fiscal 2024. I will now turn to our International Healthcare Solutions segment. In the quarter, International Healthcare Solutions revenue was $7.5 billion, up approximately 6% on an as-reported basis and up almost 9% on a constant currency basis due to increased sales at our European distribution business. International Healthcare Solutions operating income was $182 million, down 3% on an as-reported basis and up 3% on a constant currency basis.
In the quarter, lower operating income at our global specialty logistics business was partially offset by better results at our European distribution business. Our global specialty logistics business had a strong quarter in the prior year period, and this quarter was more challenging as clinical trial activity remains subdued. The business remains focused on its pipeline and targeted in its regional prioritization of new volume growth we expect to see business performance improve later in fiscal 2025 as demand for our premium service capabilities increases from its current levels.
That completes the review of our segment level results I will now discuss our updated fiscal 2025 guidance expectations. As a reminder, we do not provide forward-looking guidance for certain metrics on a GAAP basis. So the following information is provided on an adjusted non-GAAP basis, except with respect to revenue, I will also provide certain guidance metrics on a constant currency basis. I will start with adjusted diluted EPS guidance and then provide detail on the income statement items contributing to the increase.
On January 2, we announced the closing of the RCA acquisition and raised our adjusted diluted EPS guidance to the range of $15.15 to $15.45 to reflect the 9-month contribution from RCA. In addition, to continued momentum in the U.S. Healthcare Solutions segment. Today, we are pleased to again raise our full year diluted EPS guidance to a range of $15.25 to $15.55, a $0.10 increase to both the top and bottom end of our adjusted diluted EPS guidance range to better reflect the strength and momentum exhibited by the U.S. Healthcare Solutions segment. Now moving to revenue.
We expect consolidated revenue growth to be in the range of 8% to 10%, up from the previous expectations of 7% to 9% and the updated guidance range primarily reflects an increase in our U.S. Healthcare Solutions segment revenue growth, where we now expect growth of 9% to 11% and up from our previous expectations of 7% to 9% growth due primarily to continued strong organic revenue growth and to a lesser extent, RCA, which was already a distribution customer.
In the International Healthcare Solutions segment, we now expect revenue growth in the range of 4% to 5%, down from the previous range of 7% to 9% to reflect updated foreign currency translation rates. On a constant currency basis, International Healthcare Solutions segment revenue guidance remains unchanged at 7% to 9% growth.
Moving to operating income. We expect consolidated operating income growth to be in the range of 11.5% to 13.5%, up from our previous guidance of 5% to 6.5% and in the U.S. Healthcare Solutions segment, we now expect operating income growth to be in the range of 14.5% to 16.5%, up from our prior range of 5% to 6.5%. And once again, segment-level guidance reflects expected contributions from our acquisition of RCA and continued strong broad-based growth in the segment, more than offsetting previously discussed COVID-related headwinds.
Turning now to the International Healthcare Solutions segment. On an as-reported basis, we now expect operating income growth to be flat year-over-year due to the strengthening of the U.S. dollar against other currencies, and lowering the top end of our expectations for the segment. On a constant currency basis, we now expect segment operating income growth to be approximately 5%, narrowed from the previous range of 5% to 6.5% and as a result of the slower start for the International segment in the first half of fiscal year 2025.
Moving to interest expense. We now expect interest expense to be in the range of $290 million to $310 million, up from our previous range of $150 million to $170 million due to the financing of our acquisition of RCA offset in part by lower net interest expense associated with foreign subsidiaries. From a quarterly cadence perspective, we would expect interest expense to step up meaningfully in the second quarter, similar to the prior year quarter given typical seasonality and cash use as well.
Finally, we expect that our full year average share count will be under 196 million shares in fiscal 2025, given where our share count sits today. That concludes our updated full year guidance assumptions. As it relates to quarterly cadence, I would point out that we expect the second quarter to be the lowest growth quarter in fiscal 2025 with adjusted diluted EPS growth in the mid-single digits.
This is driven by a few factors. First, as I mentioned earlier, the second quarter is expected to have the highest net interest expense for the fiscal year due to typical seasonality of cash use in addition to the financing costs associated with the RCA acquisition. Second, in the U.S. Healthcare Solutions segment, we have the COVID-19 vaccine headwind and in the second quarter, which I referenced earlier and as it relates to RCA, accretion is expected to ramp over the course of the fiscal year. And finally, the slower start for the International segment in the first half of the fiscal year and the income translation impact from the strength of the U.S. dollar.
In closing, Cencora has achieved another strong quarter demonstrating the efforts of our purpose-driven team members as we continue to execute on our purpose of creating healthier futures. Their dedication and drive to the advancement of our enterprise has a proven track record of success which we see continuing in fiscal 2025 and creating value for all our customers, partners and stakeholders in the quarters to come. Now I will turn the call over to the operator to open the line for questions. Operator?
[Operator Instructions] Our first question is from Michael Cherny from Leerink Partners.
And congrats on another great quarter and guidance. Maybe just, Bob, this is your second quarter as CEO, I'll start on the strategic question, I'll say some of the other modeling ones down the road. But as you think now about your specialty business as a whole [indiscernible] clearly is a driver of some of the outperformance. As you think about the mix of market growth versus your assets, especially off the back of the OneOncology investment and now RCA, where do you think the company is best positioned to outgrow the market on specialty, how much within the guidance do you think is market-oriented growth? And where do you think going forward, the different dynamics of your specialty growth versus your peers could lie in terms of continuing to drive this potential sources of upside?
Michael, thank you very much for the question. And also hello to everyone on the call. Thank you for joining today. It's a terrific question, and I'll just -- I'll start with the strategy where we are and begin with a pharmaceutical-centered strategy, so we're going to stay focused on the pharmaceutical sector. And as you know, and as we all know, the innovation is significant there. Secondly, as we continue to build on our portfolio of services to be sure that we're well positioned both inside the United States and outside the United States to make sure that we are able to support manufacturers and providers as that specialty product growth continues over the long term. And lastly, it really begins with having the best customer portfolio in the business. And we think that's really where we're differentiated. We spend a lot of time talking about our customer portfolio, not just in specialty but broadly and believe that's a big driver of growth. If you're with the market-leading providers with the market-leading manufacturers, then that's going to position us well for growth and kind of pulling back more specifically in the expansion of services, we've spent decades building a suite of services that support community providers from GPO to analytics and many other services that we provide. And we're confident that the MSO services are the right logical next step for our strategy. It's important to providers. And it's also very much in line with where we've positioned ourselves over a long period of time. I'd just reinforce the fact that we have not only just in the specialty space, but across our portfolio, invested in services that support community providers. And this is another example of that in the part of the market where we expect to continue to lead. So again, Michael, thank you very much for the question.
Our next question is from Lisa Gill from JPMorgan.
I want to ask numbers question. When I look at the strong revenue, especially with the U.S. segment of roughly 14% in the quarter, the updated guidance is for 9% to 11%. I understand previously 7% to 9%. But can you -- how many the elements going forward are we seeing deceleration in some areas? Is it around GLP-1s, any of the store closings Walgreens or just the natural Cencora conservatism. So if you can just help us understand the cadence of that and what you're seeing as far as potential deceleration in revenue in the quarters going forward.
Lisa, thanks a lot for the question. That's an excellent question. And of course, we had terrific revenue growth in the first quarter, and you're asking about the U.S. 14% revenue growth, 10% revenue growth ex GLP-1s. And as you noted, in the U.S., we increased our revenue growth guidance by 2 percentage points at the bottom end and the top end of the range. And our guidance is 9% to 11% revenue growth for the fiscal year. But as you noted, that's lower than the revenue growth during the first quarter. And of course, we increased our adjusted operating income guidance in the U.S. by a lot more than we increased our revenue growth guidance. And I would say there are a few callouts for those sorts of things. One is our assumption in our guidance on GLP-1s is that growth is higher in the first quarter than in the balance of the fiscal year. And we'll see if that assumption is correct. Of course, we had fantastic growth on GLP-1s in the first quarter was growth. And we assume that, that growth in Q1, it's higher than it is in the balance of the year. I think the key call out here is that that particular assumption has a big impact on revenue growth but it has a minimal impact on OI. We've always indicated that GLP-1s are profitable for us, but minimally profitable for us. So really, the revenue growth assumption there doesn't have much impact on OI growth. And then second thing is our assumption is that we see [indiscernible] conversion [indiscernible]. And again, that's a revenue driver, but it has a minor impact on operating income. As we've always said, the main channel there is the lower-margin mail order channel. So again, this has a meaningful impact to revenue growth rates, but a minor impact to operating income growth rates. And then probably the third thing I would call out is the acquisition of RCA, which we feel great about, and it has a meaningful pickup for us in operating income but it's not a large revenue pickup from RCA. Again, it's a meaningful pickup in operating income but not a large pickup on the revenue side and compared to the balance of Cencora RCA is a higher margin but lower revenue business and they've already been a distribution customer. And then one kind of detailed thing I'd call out there is we don't double count the product revenue. We eliminate the sale of products from our specialty business to RCA so that we don't count the double count revenue with regard to RCA. And so overall, I'd say we feel really good about our guidance, but revenue guidance is -- the increase is not nearly the size it is for operating income, but they're due to the things that I called out, which really don't impact our strong operating income growth.
Our next question is from Elizabeth Anderson Evercore ISI.
Congrats on a really nice quarter. I had a question on sort of the World Courier business and the pharma services and sort of how you're thinking about that over the course of FY '25. Could you just maybe go into a little bit more detail about sort of what happened to [indiscernible] in the quarter and sort of how to think about that versus the rest of the year? And then broadly, sort of where do you think we are in the pharma services demand cycle? It seems like we haven't gotten too many additional pharma cuts in the last month or 2. Are we sort of getting through the cycle? I'd just be curious to hear sort of your thoughts on where we are on that.
Great. I will start out with the answer. And of course, when you're asking about World Courier in our prepared remarks, that's our global specialty logistics business and it had a more challenging quarter. And to get to your question, it was a result of clinical trial activity remaining somewhat subdued. And I will call out that this is very good business that's had strong performance for the last 10 years, I'm going to say, but in the near term, it's been challenging due to the pullback in the market. And we do expect in this business to see performance improve later in fiscal year '25 its demand for our premium service picks up. And we were with the management team of this business last week, and they're very focused on the pipeline, and they're very focused on the regions where we want to accelerate growth. And I would say, as you kind of asked the question more generally about manufacture commercialization services. And I would just say that the market is somewhat subdued, as I commented on our global specialty logistics business of Elizabeth. And I see Bob wants to add some things.
Yes. Thanks, Jim. Elizabeth, thank you very much for the question. I think just to take a step back strategically and Jim certainly handle the part of your question related to the overall pharma services market. But I do want to just reinforce how important our global footprint is to the future growth of Cencora. It really is a differentiated component of our business. We hear loud and clear from customers how important not only the specialty logistics services from World Courier are, but also our consulting services that you mentioned as well as 3PL services. And when we think about the future of specialty growth, these are services that are required and valued by the pharmaceutical manufacturers. And as you think about specialty launches in Europe, in particular, the suite of services that we have built are very well positioned to support manufacturers in that process. We hear continually that our approach to having a very local approach or a very local expertise in the markets we serve as well as a global infrastructure to support that is valued and is an important contribution to efficiency as we think about that market. So we're bullish on the strategy over the long term. We believe the market will continue to improve and we're very well positioned to participate in that improvement.
Our next question is from Steven Valiquette from Mizuho Securities.
So just a quick question in relation to Walgreens. I think no one was really surprised by this last month, but when they kind of more officially disclosed that in their earnings call that they're in active discussions with you guys in relation to the current contract. I'm just curious, I know you're probably limited on what you can say on this topic, but just open ended is there any update or additional comments that you have on this topic from your side, given their disclosures last month. And also just to confirm, your guidance presumably reflects any potential changes in that contract, at least as it pertains to your fiscal '25. I just want to confirm that 1 way or the other as well.
Yes. Thanks, Steven. I'll start and then hand it over to Jim for the guidance portion. I hope you're hearing loud and clear through our prepared remarks, Marks and other answers that partnering closely with our customers to unlock value to innovate as a core part of what we do, and you should certainly expect that we're doing that with Walgreens on a continuous basis. So we're very engaged with them. We're looking for opportunities to create value. win-win value as we go forward. We're obviously a very important -- they're a very important customer, a strategic customer over a long term, not just in the U.S., but in the U.K. as well as our sourcing relationship with WBAD. So a very high priority for us. But again, as we would with all of our most important, our teams are engaged, we're bringing the best experts that we can world-class experts in terms of trying to innovate together and create new value.
And then just to quickly answer the last part of your question. Yes, our guidance that we announced today includes our assumptions on all aspects of our business. Walgreens and every other aspect of our business, Steven.
Our next question is from Eric Percher from Nephron Research.
Bob, you mentioned that you studied the MSO business with OneOncology in real time. And I'd be interested in your perspectives on the challenges we've seen in practice management 20 years ago and physician enablement more recently and what's key to motivating and growing practices. And then, Jim, on the financial mechanics of RCA, I want to make sure we understand how much of a retention element is paid out, and we're seeing the accretion in U.S. health care, but I assume that's flowing through minority interest.
Yes. Thanks for the question, Eric. Yes, we're spending a lot of time learning. You remember in our investment in OneOncology, we did that with TPG, we're very happy with that decision and helps us continue to learn. But there are a few things that I would take away that are, I think, connected to your question. One is that the physician leadership of these MSOs is very important. And that's not in the absence of other managers and other leaders, but keeping the entire physician-based engaged and motivated. -- we're confident that strong physician leadership is important. Second is the real beauty of the MSO model is it is -- its intent, it's value creation. So it's -- it could be through new services like clinical trial support, which RCA is particularly good at, it can be through analytics and other solutions that help the physicians practice better or more efficiently for their patients and really trying to drive the best possible outcomes. And I think third is a long-term pathway for physicians who are coming into the model. So there certainly are these practices that can have long tenured physicians in them. And they're also -- it's very important that we're able to attract either smaller practices or new physicians into the MSO and both OneOncology and RCA are particularly good at that, attracting the smaller practices as well as physicians right out of fellowship.
Yes. And then I'll answer the last part of your question, Eric. As you know, we acquired RCA on January 2 at the beginning of our Q2 and our updated guidance reflects RCA. And of course, it's a big reason for our increase in our operating income growth rate in the U.S. And you'll see that all presented and the details of that when we begin reporting quarters with them in our results starting in Q2.
Our next question is from Daniel Grosslight from Citi.
Congrats on the strong quarter here. I'll stick with the MSO topic. I'm sure you saw this, but one of your competitors made an acquisition in the ophthalmology focused MSO space. I was wondering if you could talk a little bit about the competitive environment within the MSO space specifically, ophthalmology and retina, both from competition from MSO assets as you seek to acquire those. And for the physicians, affiliated physicians as you try to attract more of those to your MSS.
Thanks, Daniel. Yes, I can only speak to where we're focused, and we are very confident in that in Retina Consultants of America. We have the leading retina MSO and not just leading in terms of size, but leading in terms of their management team leading in terms of the clinical excellence, the the prominence of the practices that are within that. And as I mentioned in the previous question, also a robust clinical research network. So those are the reasons that we're confident that in that case, we'll be able to continue to attract physicians and and practices to that platform. And the very same things are true with OneOncology. We believe we have the leading platform. It's the right model. They're successfully growing. And again, it's because of the model that they've built and the services that they're providing that they continue to add practices. So Look, we've talked a lot about why this is the right strategy for Cencora. So it's not surprising to us that we would see others in our space, executing in a similar manner. But again, we're really happy and confident in the partners that we've chosen and we'll continue to execute upon that.
Our next question comes from Stephen Baxter from Wells Fargo.
I was hoping you might be willing to give us an update on what the guidance revision for the U.S. business would have been on an organic basis? Just trying to compare that on an apples-to-apples basis. And similarly, when we think about the accretion from RCA that you're going to get in this fiscal year, it sounds like it's not quite as simple as just taking the $0.35 and scaling it based on the 9 months. But maybe just give us a better sense of kind of the ramping in the second quarter and when we're going to get closer to that full rate.
Yes. And so great questions. The first one was on guidance. And let me just say, we don't specifically break it out the was. But with regard to our U.S. segment, it obviously had a a very strong first quarter, and we see quite good momentum in the U.S. segment. And of course, it's not just due to RCA. It's due to utilization trends. It's due to very broad-based performance in specialty, but in other businesses also overcoming the COVID headwind that we talked about. And I guess specifically, what I'll say is that we talked twice about updating our guidance and improving our guidance because of strength in the U.S. segment. So it's quite safe to say that it's above the performance that we're seeing there ex RCA is above the 5% to 6.5% range above that range that we initially did in our guidance. And the second question you had was regarding RCA accretion. And as we've stated, we expect $0.35 of accretion in during the first 12 months of ownership and 9 months of that is, of course, in fiscal year '25. And I referred to the fact that we do expect it to ramp up over the course of fiscal year '25. And really, the reason for that ramp-up over the course of the year is just growth in the business and then also execution of business and strategic initiatives at RCA.
Our next question is from Charles Rhyee from TD Cowen.
I wanted to ask about going back to sort of the specialty business and related to if I'm not mistaken, right, I think you guys are the largest distributor for Regeneron on EYLEA. And Amgen just launched, I think they announced last quarter, the launch of their version Pat Blue into the market. And I think there's another one supposed to be coming maybe this summer. Just curious, those scripts are kind of hard to track through sources like [indiscernible] just wanted to understand how that launch is going for you? And what kind of opportunity do you see biosimilar EYLEA being? And how does your ownership of RCA perhaps allow you to -- does that allow you to drive better adoption of biosimilars? And I guess that's a more general question across all your M&A practices.
Charles, thanks for the question. So I'll start with -- we've had a long history of partnering with retina physicians over decades. And so we do understand the space very well. Two, we have studied the the pipelines pretty extensively or very extensively in terms of new innovation as well as biosimilars, and we're confident that, that will be a healthy process. So we'll have continuous new innovation. We'll also that come to the market, and that's a healthy market. That will be good for patients. It will be good for the MSO and good for Cencora. And I think lastly, what we've seen over both in oncology and coming in retina is that biosimilar adoption is good. It's in the Part B space, it's our experience has been it's faster than you see in the Part D space. And we expect that will continue. But I think the most important part of this is just a healthy market, continuous innovation as well as appropriate biosimilars coming to the market. And then physicians will obviously make the best clinical decision for the patients that they're carried for [indiscernible].
Our next question is from Allen Lutz from Bank of America.
As we kind of look back to 2024, utilization was really strong in U.S. health care. I think we've seen that broad across the different distributors. And some of that, I think, was due to just sort of this post-COVID reacceleration of scripts as patients are going back to the physician. There were a few things you called out, GLP-1s than HUMIRA. If we back those things out, how should we think about new script growth more broadly in 2025 versus 2024. Is -- what's embedded in the current guidance a normalization of utilization. Is there anything that you're seeing from the benefit design changes that were put forth on January 1. Just curious if there's anything embedded within the guide outside of the things you called out that is a little bit different in 2025 versus 2024?
Yes. That's a great question. And as we commented throughout fiscal year '24, we saw strong utilization trends. And as we called out during this first quarter, we also saw strong utilization trends. And I would just have to say kind of as you look at the balance of fiscal year '25, this is why we have a range kind of probably the kind of the key driver in our range and our range is, of course, 2 full percentage points for both consolidated and the U.S. top line growth and probably, by far, the biggest driver of that range is various assumptions on utilization trends for the balance of the year. But I just want to say overall, that kind of we view our -- both our company performance and leading with market leaders and the strength of our market is quite good and quite resilient, which is one thing that gives us a high degree of confidence in our guidance for fiscal year '25. Thank you for the question.
Our next question is from George Hill from Deutsche Bank.
I'm going to come back to the MSO businesses for a second. And Jim, you talked about the clinical trial component. But what I was going to ask is could you rank order the value drivers that allow, whether it's Cencora or RCA or OneOncology to add value to its physician partners in these practices. Like we know GPL was a piece, clinical trials, is a piece to recycle the piece. Just like if you could kind of lang out the 3 or 4 main drivers of value creation, I think that would be very helpful for investors.
George, it's Bob. I'll take this. I don't think we can rank them necessarily. And within the different physician practices within the different specialties, I think there's a different mix of things that are valuable to those physicians and those are going to be the value drivers. And probably the second point of that is it's continually changing, right? So it's a very dynamic marketplace, the needs of physicians are always changing. And that's one of the great things about having the robust suite of MSO services is you have the infrastructure then to make sure that we're doing our best to keep up with and stay a step ahead of what they need and kind of that same approach that we've been emphasizing, which is working really closely with our customers to to bring solutions and innovation to the market. Again, we do that across all of our business, but the MSO platform gives us an opportunity, obviously, even a step closer to the provider to do that on a continuous basis, which will be our intent.
Our next question is from Erin Wright from Morgan Stanley.
I think you mentioned specialty strength was broad-based, but any key therapeutic categories to call out there? And if I can ask a 2-parter here I'm switching species, but I'm just curious what you're seeing in animal health. There seems to be just a lot of promotion in the space and competition at both the manufacturer and the distributor level to some extent. And just bigger picture, it's been roughly 10 years in the MWI deal close? And how would you characterize how you see MWI sitting in the enterprise now, your commitment to the business does it detract at all from some of the broader efforts and long-term vision across like specialty or your MSO strategy? And just curious on your bigger picture thoughts there.
Yes. Thank you for those questions. First of all, your question was on specialty. And our specialty business is always kind of the biggest driver has always been the oncology part of the business. And obviously, a very strong part of that for Cencora is in Part B in our sales to specialty physician practices and health systems. So that's really kind of been the kind of the key driver of the business. And then the kind of second piece has been in the ophthalmology space. And in particular, the retinal space. And so that's exactly why you've seen our significant capital deployment into NSOs, first in oncology and then the retina market, which as Bob commented on, is really kind of a natural evolution and next step of our highly successful specialty business. And then thank you for your question on Animal Health. Our Animal Health business had a very good quarter. You'll see in our Q that will be published later today. The Animal Health business had 7% top line growth. And the growth was -- and while we don't break it out, the growth was actually good in the quarter in both the companion animal market, which is about 2/3 of our business in the production animal market, which is about 1/3 of our business, both had both had very nice growth quarters. And not only was it good top line growth, but good bottom line growth in the business also. A part of that is probably the market, but I think we're probably continuing to incrementally gain some market share there. And also, I'd just say we feel very good about the animal health business. and feel that the management team there is doing a particularly good job. So thank you for the questions, Aaron.
Our next question is from Kevin Caliendo from UBS.
Does your fiscal '25 guidance embed any incremental customer loss beyond FCS. I know you detailed that back in November. That was the first part. And just specifically on the [indiscernible] or the COVID headwind, was it better or worse than expectations in fiscal 1Q?
Can you say -- we missed the last part of your question. Can you repeat that?
I'm sorry. Yes, sure. No, just on the COVID headwind, was it better or worse than expectations? In fiscal 1Q versus what you originally thought when you originally guided?
Yes. So the first was, I think, our guidance does it impact -- does it expect any customer losses other than the one that you mentioned. And I would say, generally, the answer is yes, it assumes some customer losses and games. But really, there's none other than the one you called out that's a meaningful amount of profit or loss that would be worth calling out. And so we don't call it out. And then the second question had to do with COVID. And with regard to exclusive COVID therapies, which is I think what you're asking about is it was a $0.06 headwind during the first quarter, but the first quarter of fiscal year '24 was the last quarter that we had exclusive COVID therapy contribution. So it's not a headwind for the balance of the year. And with regard to COVID vaccines, we really called this out in our prepared remarks that in the first quarter of fiscal 2025, the contribution from COVID-19 vaccines was about half that of the prior year quarter. And we expect a similar sized operating income headwind in the second quarter of fiscal 2025, meaning no significant expected contribution from COVID vaccines in our second quarter of fiscal 2025. And so the strong guidance raise and increase that we did this quarter is in spite of that COVID vaccine headwind. Thank you for the questions.
Our next question is from Eric Coldwell from Baird.
I didn't think World Courier could get this much attention on the call, but I do have some world courier questions. First, I wouldn't disagree that there are some market challenges subdued clinical trial activity that all makes sense for the softness you cited. You also do cell and gene therapy and other specialty shipments unrelated to clinical trials. So I'm wondering how those are faring Part B, what is the basis for saying clinical trial activity will pick up later this year and Part C on World Courier any additional commentary on competition in the market? We've seen some noise from UPS Healthcare and others. I just want to make sure that the weakness in World Courier is more temporary and end market related as opposed to something going on in the competitive front?
Yes, let me start out here. First of all, we feel very good about the opportunities in the cell and gene therapy market. And it's a result of our World Courier strength, Eric, and then the strength in our other commercialization services businesses. So as we look at the long term, and we feel great about that market opportunity, and we feel very good about how well positioned we are to be the leader in the market. But I would say that it's not of a size yet, but it has a material contribution to the bottom line. Second, you ask, why do we think that there's opportunity to see improvement in global specialty logistics later in the fiscal year. And meeting with the teams and looking at market data and looking at the pipeline, our teams are really heavily focused on the pipeline, which we feel has the opportunity to pay off later in the fiscal year, given both the market and given the work that our teams are doing. And then the third part of the question was on competition. And yes, that market it certainly is a competitive market. We have a premium service and have been a market leader for many years and are very focused on the market, but we will acknowledge that it certainly is a competitive market where we have been and plan to continue to be a market leader.
Yes. And Eric, I would only add -- and again, this is thematic today, but being a premium provider indicates that we're continually innovating within that space. So the things that we've talked about in terms of temperature monitoring and tracking of of products throughout the supply chain, a very specialized supply chain for these products. It's something that we'll continue to do that's just an example. But while there is competition, we intend to continue to innovate to make sure that we're we're ahead of the pack.
Thank you. We currently have no further questions. So I'll hand back to Bob for closing remarks.
Great. Thank you, Becky. Again, I want to thank everyone for joining today. I also want to thank again our Cencora team members. This performance is due to your purpose-driven approach, your expertise and your dedication to meeting the needs of our customers and patients worldwide. And I know you will continue to advance our leadership in specialty, drive efficiency and productivity and execute with a customer-centric mindset. Thanks, everyone.
This concludes today's call. Thank you for joining. You may now disconnect your lines.