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Iterum Therapeutics PLC
NASDAQ:ITRM

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Iterum Therapeutics PLC Logo
Iterum Therapeutics PLC
NASDAQ:ITRM
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Price: 0.016 USD 15.11%
Market Cap: $852.6k

EV/EBITDA

-1.2
Current
70%
More Expensive
vs 3-y median of -0.7

Enterprise Value to EBITDA (EV/EBITDA) ratio compares a company`s total enterprise value to its earnings before interest, taxes, depreciation, and amortization. It shows how much investors are paying for each dollar of the company`s earnings, including both equity and debt.

EV/EBITDA
-1.2
=
Enterprise Value
$23.9m
/
EBITDA
$-19.3m

Enterprise Value to EBITDA (EV/EBITDA) ratio compares a company`s total enterprise value to its earnings before interest, taxes, depreciation, and amortization. It shows how much investors are paying for each dollar of the company`s earnings, including both equity and debt.

EV/EBITDA
-1.2
=
Enterprise Value
$23.9m
/
EBITDA
$-19.3m

Valuation Scenarios

Iterum Therapeutics PLC is trading above its industry average

If EV/EBITDA returns to its Industry Average (11), the stock would be worth $-0.15 (1 020% downside from current price).

Statistics
Positive Scenarios
0/2
Maximum Downside
-1 020%
Maximum Upside
No Upside Scenarios
Average Downside
1 001%
Scenario EV/EBITDA Value Implied Price Upside/Downside
Current Multiple -1.2 $0.02
0%
Industry Average 11 $-0.15
-1 020%
Country Average 10.6 $-0.14
-982%

Forward EV/EBITDA
Today’s price vs future ebitda

Today's Enterprise Value EBITDA Forward EV/EBITDA
$23.9m
/
Oct 2025
$-19.3m
=
-1.2
Current
$23.9m
/
Dec 2025
$-25.6m
=
-0.9
Forward
$23.9m
/
Dec 2026
$-16.5m
=
-1.4
Forward
$23.9m
/
Dec 2027
$25.4m
=
0.9
Forward

Forward EV/EBITDA shows whether today’s EV/EBITDA still looks high or low once future ebitda are taken into account.

Peer Comparison

All Multiples
EV/EBITDA
P/E
All Countries
Close
Market Cap EV/EBITDA P/E
IE
Iterum Therapeutics PLC
NASDAQ:ITRM
783.9k USD -1.2 -0
US
Eli Lilly and Co
NYSE:LLY
878.2B USD 28.6 42.3
US
Johnson & Johnson
NYSE:JNJ
573B USD 15 21.6
CH
Roche Holding AG
SIX:ROG
248.4B CHF 11.6 19.6
UK
AstraZeneca PLC
LSE:AZN
231.4B GBP 16.6 30
US
Merck & Co Inc
NYSE:MRK
297.3B USD 10.1 16.2
CH
Novartis AG
SIX:NOVN
231.4B CHF 12.8 20.7
IE
Endo International PLC
LSE:0Y5F
244.4B USD 386.8 -83.6
DK
Novo Nordisk A/S
CSE:NOVO B
1.1T DKK 7.9 10.7
US
Pfizer Inc
NYSE:PFE
155.5B USD 7.7 19.9
UK
GlaxoSmithKline PLC
LSE:GSK
89.3B GBP 8.4 15.6
EV/EBITDA Multiple
EBITDA Growth EV/EBITDA to Growth
IE
Iterum Therapeutics PLC
NASDAQ:ITRM
Average EV/EBITDA: 50.5
Negative Multiple: -1.2
N/A N/A
US
Eli Lilly and Co
NYSE:LLY
28.6
21%
1.4
US
Johnson & Johnson
NYSE:JNJ
15
2%
7.5
CH
Roche Holding AG
SIX:ROG
11.6
6%
1.9
UK
AstraZeneca PLC
LSE:AZN
16.6
12%
1.4
US
Merck & Co Inc
NYSE:MRK
10.1
4%
2.5
CH
Novartis AG
SIX:NOVN
12.8
5%
2.6
IE
E
Endo International PLC
LSE:0Y5F
386.8
N/A N/A
DK
Novo Nordisk A/S
CSE:NOVO B
7.9
2%
4
US
Pfizer Inc
NYSE:PFE
7.7
-8%
N/A
UK
GlaxoSmithKline PLC
LSE:GSK
8.4
3%
2.8
P/E Multiple
Earnings Growth PEG
IE
Iterum Therapeutics PLC
NASDAQ:ITRM
Average P/E: 21.8
Negative Multiple: -0
N/A N/A
US
Eli Lilly and Co
NYSE:LLY
42.3
31%
1.4
US
Johnson & Johnson
NYSE:JNJ
21.6
8%
2.7
CH
Roche Holding AG
SIX:ROG
19.6
14%
1.4
UK
AstraZeneca PLC
LSE:AZN
30
25%
1.2
US
Merck & Co Inc
NYSE:MRK
16.2
14%
1.2
CH
Novartis AG
SIX:NOVN
20.7
14%
1.5
IE
E
Endo International PLC
LSE:0Y5F
Negative Multiple: -83.6 N/A N/A
DK
Novo Nordisk A/S
CSE:NOVO B
10.7
0%
N/A
US
Pfizer Inc
NYSE:PFE
19.9
22%
0.9
UK
GlaxoSmithKline PLC
LSE:GSK
15.6
14%
1.1

Market Distribution

Lower than 100% of companies in Ireland
Percentile
0th
Based on 255 companies
0th percentile
-1.2
Low
0 — 6
Typical Range
6 — 12.9
High
12.9 —
Distribution Statistics
Ireland
Min 0
30th Percentile 6
Median 10.6
70th Percentile 12.9
Max 338.7

Iterum Therapeutics PLC
Glance View

Market Cap
852.6k USD
Industry
Pharmaceuticals

Iterum Therapeutics Plc operates as a pharmaceutical company, which engages in the development and commercialization of sulopenem to be potentially the first and only oral and intravenous (IV) branded penem available. The company is headquartered in Dublin, Dublin and currently employs 13 full-time employees. The company went IPO on 2018-05-25. The firm is focused on developing significantly differentiated anti-infectives aimed at combatting the global crisis of multi-drug resistant (MDR) pathogens. The firm is developing sulopenem - the oral and intervenous (IV) penem antibiotic demonstrating a potent spectrum of activity against multi-drug resistant gram-negative. The company is a bioavailable, antibiotic covering gram-positive, gram-negative and anaerobic pathogen with in-vitro activity against multidrug-resistant pathogens, including Extended-Spectrum Beta-Lactamase (ESBL)-producing Escherichia, coli and Klebsiella and pneumonia. The firm also developed sulopenem in an oral tablet formulation, sulopenem etzadroxil-probenecid, which is known as oral sulopenem.

ITRM Intrinsic Value
Not Available
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