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Axsome Therapeutics Inc
NASDAQ:AXSM

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Axsome Therapeutics Inc
NASDAQ:AXSM
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Price: 182.97 USD -3.03% Market Closed
Market Cap: $9.4B

EV/EBIT

-54.3
Current
198%
More Expensive
vs 3-y average of -18.2

Enterprise Value to EBIT (EV/EBIT) ratio compares a company`s total enterprise value to its earnings before interest and taxes. It shows how much investors are paying for each dollar of the company`s earnings, including both equity and debt.

EV/EBIT
-54.3
=
Enterprise Value
$8.5B
/
EBIT
$-169.1m

Enterprise Value to EBIT (EV/EBIT) ratio compares a company`s total enterprise value to its earnings before interest and taxes. It shows how much investors are paying for each dollar of the company`s earnings, including both equity and debt.

EV/EBIT
-54.3
=
Enterprise Value
$8.5B
/
EBIT
$-169.1m

Valuation Scenarios

Axsome Therapeutics Inc is trading above its industry average

If EV/EBIT returns to its Industry Average (12.1), the stock would be worth $-40.76 (122% downside from current price).

Statistics
Positive Scenarios
0/2
Maximum Downside
-136%
Maximum Upside
No Upside Scenarios
Average Downside
129%
Scenario EV/EBIT Value Implied Price Upside/Downside
Current Multiple -54.3 $182.97
0%
Industry Average 12.1 $-40.76
-122%
Country Average 19.6 $-66.12
-136%

Forward EV/EBIT
Today’s price vs future ebit

Today's Enterprise Value EBIT Forward EV/EBIT
$8.5B
/
Jan 2026
$-169.1m
=
-54.3
Current
$8.5B
/
Dec 2026
$-25m
=
-339.6
Forward
$8.5B
/
Dec 2027
$383.1m
=
22.2
Forward
$8.5B
/
Dec 2028
$831.1m
=
10.2
Forward

Forward EV/EBIT shows whether today’s EV/EBIT still looks high or low once future ebit are taken into account.

Peer Comparison

All Multiples
EV/EBIT
P/E
All Countries
Close
Market Cap EV/EBIT P/E
US
Axsome Therapeutics Inc
NASDAQ:AXSM
9.3B USD -54.3 -50.8
US
Eli Lilly and Co
NYSE:LLY
853.2B USD 29.8 41.3
US
Johnson & Johnson
NYSE:JNJ
544.6B USD 21.2 25.9
CH
Roche Holding AG
SIX:ROG
248.4B CHF 13.2 19.8
UK
AstraZeneca PLC
LSE:AZN
225.8B GBP 22.8 29.2
CH
Novartis AG
SIX:NOVN
226.8B CHF 15.9 19.9
US
Merck & Co Inc
NYSE:MRK
278.5B USD 11.6 15.3
IE
Endo International PLC
LSE:0Y5F
244.4B USD 970 -83.6
DK
Novo Nordisk A/S
CSE:NOVO B
1.1T DKK 9.4 10.9
US
Pfizer Inc
NYSE:PFE
155.3B USD 10.2 20
US
Bristol-Myers Squibb Co
NYSE:BMY
119.6B USD 8.8 17
EV/EBIT Multiple
EBIT Growth EV/EBIT to Growth
US
Axsome Therapeutics Inc
NASDAQ:AXSM
Average EV/EBIT: 111.3
Negative Multiple: -54.3
N/A N/A
US
Eli Lilly and Co
NYSE:LLY
29.8
22%
1.4
US
Johnson & Johnson
NYSE:JNJ
21.2
13%
1.6
CH
Roche Holding AG
SIX:ROG
13.2
6%
2.2
UK
AstraZeneca PLC
LSE:AZN
22.8
21%
1.1
CH
Novartis AG
SIX:NOVN
15.9
9%
1.8
US
Merck & Co Inc
NYSE:MRK
11.6
6%
1.9
IE
E
Endo International PLC
LSE:0Y5F
970
N/A N/A
DK
Novo Nordisk A/S
CSE:NOVO B
9.4
2%
4.7
US
Pfizer Inc
NYSE:PFE
10.2
-4%
N/A
US
Bristol-Myers Squibb Co
NYSE:BMY
8.8
-7%
N/A
P/E Multiple
Earnings Growth PEG
US
Axsome Therapeutics Inc
NASDAQ:AXSM
Average P/E: 22.1
Negative Multiple: -50.8
N/A N/A
US
Eli Lilly and Co
NYSE:LLY
41.3
32%
1.3
US
Johnson & Johnson
NYSE:JNJ
25.9
8%
3.2
CH
Roche Holding AG
SIX:ROG
19.8
14%
1.4
UK
AstraZeneca PLC
LSE:AZN
29.2
25%
1.2
CH
Novartis AG
SIX:NOVN
19.9
14%
1.4
US
Merck & Co Inc
NYSE:MRK
15.3
14%
1.1
IE
E
Endo International PLC
LSE:0Y5F
Negative Multiple: -83.6 N/A N/A
DK
Novo Nordisk A/S
CSE:NOVO B
10.9
0%
N/A
US
Pfizer Inc
NYSE:PFE
20
22%
0.9
US
Bristol-Myers Squibb Co
NYSE:BMY
17
16%
1.1

Market Distribution

Lower than 100% of companies in the United States of America
Percentile
0th
Based on 8 638 companies
0th percentile
-54.3
Low
0 — 13.6
Typical Range
13.6 — 27.8
High
27.8 —
Distribution Statistics
the United States of America
Min 0
30th Percentile 13.6
Median 19.6
70th Percentile 27.8
Max 1 826 183.2

Axsome Therapeutics Inc
Glance View

Axsome Therapeutics Inc. emerged as a dynamic player in the biopharmaceutical arena, driven by a resolute commitment to alleviate the burdensome effects of central nervous system (CNS) disorders. Founded with a vision to fill critical treatment gaps in neurologically influenced conditions, Axsome leverages innovative drug discovery and development to address medical needs that have long been underserved. The company focuses intently on conditions such as depression, migraine, narcolepsy, and Alzheimer's disease-related agitation, channeling resources into a streamlined pipeline that seeks to fast-track the development and commercialization of life-changing therapies. Operating at the intersection of cutting-edge science and patient-centric healthcare, Axsome generates revenue through the successful approval and marketing of its proprietary pharmaceutical products. The company's business model hinges on advancing its clinical candidates through rigorous trials, eventually gaining the necessary regulatory endorsements to bring them to market. By holding the intellectual property rights for these novel drugs, Axsome enjoys the advantages of exclusivity in the marketplace, which allows it to negotiate favorable pricing and reimbursement terms. This strategic approach not only positions Axsome as a potentially transformative force within the pharmaceutical industry but also underlines its commitment to producing viable, accessible treatments for those grappling with debilitating CNS disorders.

AXSM Intrinsic Value
170.03 USD
Overvaluation 7%
Intrinsic Value
Price $182.97
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